ASYNP123

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Entry details

aSynPEP ID

ASYNP123

Peptide name

Blood-brain barrier peptide; Exendin-4

Type

Food-derived

Source ID

DFBPBBBP0006

UniProt Accession number

P26349

Source organism

Heloderma suspectum

8554

PubMed ID

12629557

aSynPEP features

Peptide sequence

Peptide length: 39
Longest inhibitory region: 18-37
         10         20         30
 HGEGTFTSDL SKQMEEEAVR LFIEWLKNGG PSSGAPPPS

Helical wheel

Helicity (AGADIR)

42.5

Amphipathicity (uH)

0.34

NCPR

+0.1

Hydrophobicity (H)

0.49

Physicochemical properties

pI

11.375

Mass

2.1 kDa

Predicted properties

AlphaFold structural model

Download PDB

pH of order (DispHred)

Cytotoxicity (ToxIBTL)

non-toxic | probability=2.91E-09

Blood Brain Barrier permeability (BBPPred)

non-BBP | probability=0.10

Cell-penetrating (BchemRF-CPPred)

Non-CPP | probability=87.38%

Expression

Gut/brain expression

By The Human Protein Atlas

By ProteomicsDB

Pathways

PubChem